Engineering Natural and Synthetic Resistance for Nematode Management

Thierry C. Vrain


Bioengineering strategies are being developed that will provide specific and durable resistance against plant-parasitic nematodes in crops. The strategies come under three categories: (i) transfer of natural resistance genes from plants that have them to plants that do not, to mobilize the defense mechanisms in susceptible crops; (ii) interference with the biochemical signals that nematodes exchange with plants during parasitic interactions, especially those resulting in the formation of specialized feeding sites for the sedentary endoparasites--many nematode genes and many plant genes are potential targets for manipulation; and (iii) expression in plant cells of proteins toxic to nematodes.


cystatins; enzyme inhibitors; giant cells; hypersensitivity; lectins; natural resistance genes; nematodes; nematode genes; nematode-induced promoters; plant defense; plant genes; syncitia; synthetic resistance; toxins; transformation; transgenic plants

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